Biotech Firm Curates 115% Gains on Cancer Trial Win

A social media firm posted strong ad revenue and a jump in global users, a travel booking giant is stumbling after missing revenue estimates, and a cancer-focused biotech is surging 115% on positive trial results. Read on to find out more.

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Futures 📈

What to Watch

Earnings:

• None Scheduled

Economic Reports:

• Fed Gov. Michael Barr speech: 5:55 am

• Fed Gov. Adriana Kugler speech: 6:45 am

• NY Fed Pres. John Williams speech: 8:30 am

• Richmond Fed Pres. Tom Barkin speech: 8:30 am

• Chicago Fed Pres. Austan Goolsbee speech: 10:00 am

• Fed Gov. Christopher Waller & NY Fed Pres. John Williams panel: 11:30 am

• Fed Gov. Lisa Cook speech: 6:45 am

• Fed Gov. Michelle Bowman, St. Louis Fed Pres. Alberto Musalem & Cleveland Fed Pres. Beth Hammack panel: 7:45 pm

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Social Media

Pinterest Jumps 12% as Ad Sales Thrive Despite Tariff Concerns

Pinterest (NYSE: PINS) is surging more than 12% in premarket trading after reporting better-than-expected quarterly revenue and user growth, easing investor concerns about digital ad spending amid global economic uncertainty.

The social media platform reported a 10% year-over-year increase in global monthly active users, reaching 570 million—topping analyst expectations, according to LSEG data.

The performance places Pinterest in league with digital peers like Reddit (NYSE: RDDT) and Meta Platforms (NASDAQ: META), both of which also posted strong advertising results in the face of slowing global trade and inflation fears.

Headwinds from recent changes in U.S. trade policy and a rollback of the "de minimis" exemption—impacting Chinese advertisers like Shein and Temu—has hurt e-commerce players.

However, Pinterest has benefited from its focus on improving AI tools for ad personalization and expanding its Gen Z user base.

Pinterest's international momentum and improved shopping-related features as key drivers of growth are part of the reason behind its success.

However, there is a possibility of pressure on e-commerce ad spending if tariffs weigh further on consumer behavior.

If the stock holds its premarket gains, Pinterest is poised to add more than $2.5 billion to its market value.

Travel

Soft Domestic Travel Hits Expedia, Shares Slide Over 9%

Expedia Group (NASDAQ: EXPE) shares are dropping more than 9% in premarket trading after missing first-quarter revenue expectations, reflecting softer-than-anticipated travel demand in the U.S. market.

The company reported revenue of $2.98 billion for the quarter ending March 31, falling short of analyst forecasts of $3.01 billion, according to data from LSEG.

Despite the miss on sales, adjusted earnings came in at $0.40 per share, topping the expected $0.32 per share.

Expedia’s significant U.S. exposure is one of the key reasons for the pronounced impact.

As economic uncertainty driven by ongoing tariff disputes and high interest rates dampens consumer confidence, the travel sector is beginning to feel pressure ahead of the critical summer season.

Peer companies are also showing signs of strain. Hilton recently trimmed its full-year revenue outlook, and Airbnb noted a shorter booking window, hinting at greater hesitation among travelers.

Expedia is down 10.05% in premarket trade. Year-to-date, Expedia’s stock is down 9.3%, underperforming the S&P 500’s 3.7% decline.

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Medical Technology

TransMedics Stock Jumps on Strong Q1 Results and Upbeat Forecast

TransMedics Group (NASDAQ: TMDX) reported first-quarter earnings that more than doubled year-over-year and significantly topped analyst expectations, prompting a 16.7% surge in the stock during after-hours trading Thursday.

The medical technology firm posted earnings of $0.70 per diluted share for the quarter ending March 31, a sharp increase from $0.35 a year ago and well above the $0.26 consensus estimate from analysts surveyed by FactSet.

Revenue also beat forecasts, reaching $143.5 million—up from $96.9 million in the same period last year and outpacing the projected $123.7 million.

The strong performance reflects growing demand for the company’s organ transplant technology and services.

Buoyed by the strong start to the year, TransMedics raised its full-year revenue outlook.

The company now expects 2025 revenue between $565 million and $585 million, up from its prior estimate of $530 million to $552 million. The new range is well ahead of Wall Street’s $559.4 million forecast.

The upbeat report reinforces investor confidence in TransMedics' momentum in the organ care space and its ability to scale operations while driving profitability.

Shuttle Pharmaceuticals Holdings [SHPH] - Last Close: $0.27

Shuttle Pharmaceuticals Holdings is a clinical-stage biotech firm developing radiation sensitizers like Ropidoxuridine to enhance cancer treatment outcomes.

The stock is up over 115% in premarket trading today because SHPH has nearly reached 50% enrollment in its Phase 2 glioblastoma trial, with the drug showing favorable tolerance and adherence, boosting investor confidence.

Webuy Global Ltd. [WBUY] - Last Close: $7.11

Webuy Global Ltd. is a Singapore-based e-commerce platform that leverages social buying to offer group discounts, with a growing focus on travel services. After being delisted in January, the stock was recently relisted on Nasdaq.

The stock surged +132% yesterday following its reinstatement on the Nasdaq Capital Market and is continuing to rise in premarket today.

The primary reason is its robust growth in Q1, specifically in its travel segment. It reported over $2.6 million in travel bookings, marking a 45% year-over-year increase, and achieved its first-ever quarterly profit.

Corvus Pharmaceuticals, Inc. [CRVS] - Last Close: $3.35

Corvus Pharmaceuticals is a clinical-stage biotech firm developing immune-modulating therapies for cancer and autoimmune diseases.

The stock is up over 34% in premarket trading today following favorable interim Phase 1 trial results for soquelitinib in atopic dermatitis, particularly at the 200 mg twice-daily dosage.

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*Disclaimer: All individual claims are independent views, and the result may vary as per potential & caliber
(from person to person). Results may not be typical nor expected for every person. This is not a "get rich quick" scheme. All information provided on this website and webinar is based on best practices and for educational-purposes only. We are publishers, not licensed financial advisors. Information provided is for informational purposes only and is not intended as financial advice. Always consult a professional advisor for personalized financial guidance.

Everything Else

• McKesson’s stock jumps after an earnings beat and a surprise spin-off plan.

• Monster sales slide as U.S. consumers pull back and bottler demand shifts.

• Crypto volatility drags down Coinbase Q1 revenue despite legal and product wins.

• Cloudflare leads a tech trio higher with new security tools and AI ambitions.

• Mitsubishi Heavy looks past tariff risks with an optimistic defense-led outlook.

• Chinese exports soar on Southeast Asia boost, even as U.S. trade sinks under tariffs.

• SMIC stumbles despite soaring demand, as U.S. restrictions and missed targets weigh.

That’s all for today. Thank you for reading. If you have any feedback, please reply to this email.

Best Regards,

— Adam Garcia
Elite Trade Club

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