A major upgrade in in-flight connectivity and encouraging cancer trial data fueled outsized gains, while dilution concerns and longer development timelines weighed heavily on others.

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Markets
U.S. stocks were mixed as the recent rally in tech and chipmakers paused, while strength in consumer and energy stocks helped offset broader losses ahead of Friday’s key jobs report.
DJIA [+0.55%]
S&P 500 [+0.01%]
Nasdaq [-0.44%]
Russell 2k [+1.08%]

Market-Moving News
Power Generation
This Deal Quietly Rewrites B&W’s Future

Babcock & Wilcox (NYSE: BW) has just made a move that pulls it straight into the heart of the AI infrastructure boom, locking in a deep partnership with Siemens Energy to deliver massive, on-demand power for next-generation data centers.
This is not a side project. It is B&W stepping into a constraint that could decide how fast AI scales.
At the center is a one-gigawatt power build tied to an Applied Digital AI factory, powered by multiple natural gas plants built specifically for high-density computing.
These systems are designed for stability first, because if you are running AI at scale, power hiccups are not an option.
B&W Changes What It Is
This partnership pushes B&W far beyond its old industrial image. When paired with Siemens Energy turbines, the company becomes a full-solution provider for AI power infrastructure.
B&W is inserting itself into the decisions you know hyperscalers care about most: reliability, timing, and control.
The Constraint Everyone Is Chasing
As AI grows, electricity becomes the bottleneck. Chips alone do not win.
By solving power delivery early, B&W gains relevance in one of the fastest-growing infrastructure cycles ahead.
And if you are thinking long term, this is a company choosing to grow where the pressure is highest and the demand is locked in.

Pharmaceuticals
Vanda Slams Into a Hard FDA Reality Check

Vanda Pharmaceuticals (NASDAQ: VNDA) just hit a wall in its effort to expand HETLIOZ into jet lag treatment, after the FDA declined approval and stopped what could have been a major growth unlock.
This is not a safety issue and not a manufacturing problem. It is the FDA saying the evidence did not feel real enough.
The agency acknowledged positive trial signals, but rejected the idea that simulated sleep shifts truly represent what happens when you fly across time zones.
No cabin pressure, no cramped seats, no hours stuck in the air. If you have ever landed exhausted and disoriented, you already understand the gap regulators are pointing to.
The Missed Step Change
HETLIOZ remains approved for Non-24 sleep disorder and Smith-Magenis Syndrome, but jet lag was different. It was the chance to move from niche medicine to mainstream relevance.
Jet lag affects millions of travelers every year. Approval would have reshaped Vanda’s commercial profile overnight, and you can see why this decision stings.
Strategy Gets Tested Here
Now Vanda faces a fork in the road. Redesign studies to satisfy regulators, or refocus on pipeline assets and existing indications.
This moment is a reminder that in biopharma, growth often hinges on persuasion, not discovery. And if you are watching closely, this is where execution and regulatory strategy decide whether ambition turns into scale or stays grounded.

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Autonomous Systems
NVIDIA Pushes AI Off the Screen and Into the Real World

NVIDIA (NASDAQ: NVDA) just took a major step in redefining what artificial intelligence actually does, unveiling Alpamayo, a new Physical AI system built to help machines perceive, reason, and act in messy real-world environments.
This is not another software layer for data centers. It is Nvidia pushing intelligence directly into motion.
Alpamayo combines vision, language, and action into a single reasoning stack designed for edge cases, not perfect conditions.
If you have ever seen autonomy fail the moment something unexpected happens, you understand why this matters.
AI Finally Learns to Deal With Reality
Most AI works great in controlled settings. Real life is chaos. Alpamayo is designed to handle uncertainty, adapting when rules break and conditions change. That is the leap from scripted automation to systems that actually reason, and once you see that shift, the opportunity widens fast.
NVIDIA Moves Up the Stack
This launch makes something clear. NVIDIA is no longer content with being just the hardware layer. Alpamayo lowers the barrier to entry for autonomy across industries, from factories to logistics to humanoid robotics. More players can build faster, but Nvidia stays central.
As AI moves from digital answers to physical action, Nvidia is positioning itself right at the handoff point. And if you are watching where the next decade of AI value lives, this is a loud signal that Physical AI is now a core pillar, not an experiment.

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Top Winners and Losers
flyExclusive Inc [FLYX] $7.24 (+130.57%)
flyExclusive surged after signing an authorized dealership agreement with Starlink, enabling high-speed in-flight connectivity across its fleet and opening a new MRO revenue stream.
Enliven Therapeutics Inc [ELVN] $23.25 (+50.29%)
Enliven climbed after reporting strong Phase 1b data for ELVN-001 in chronic myeloid leukemia, showing high molecular response rates in heavily pretreated patients.
Neogen Corp [NEOG] $9.71 (+31.44%)
Neogen advanced after beating earnings expectations and raising full-year revenue and EBITDA guidance, signaling improving profitability despite near-term revenue pressure.

Immuneering Corp [IMRX] $4.73 (-43.22%)
Immuneering fell despite strong Phase 2a survival data in pancreatic cancer, as investors focused on the long wait until its pivotal Phase 3 trial is expected to begin in mid-2026.
CorMedix Inc [CRMD] $7.51 (-32.77%)
CorMedix slid after issuing 2026 guidance that flagged upcoming pricing pressure for DefenCath tied to changes in dialysis reimbursement.
Phathom Pharmaceuticals Inc [PHAT] $15.60 (-13.67%)
Phathom dropped after announcing a large underwritten public offering, raising dilution concerns despite solid revenue growth and improving profitability trends.

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Everything Else
Paramount is back, telling Warner Bros its bid still beats Netflix’s, keeping the deal chest-thumping alive.
U.S. stocks chopped around as traders waited on jobs data to tell them how shaky the outlook really is.
Vitol snagged a preliminary U.S. license to start talks on Venezuelan oil flows, putting barrels and politics in the same room again.
Constellation Brands warned that beer sales are feeling the squeeze as Hispanic consumers pull back spending.
Bank of America upgraded Coinbase to Buy, betting Base finally gives the stock a real growth engine.
Mortgage rates crept higher, pushing the 30-year average to 6.16 percent and cooling buyer nerves again.

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