Big Pharma is putting serious money behind its next generation of treatments, with Roche and Merck expanding their pipelines through major agreements. Meanwhile, dealmaking remains active across financial services and manufacturing, while a disappointing IPO debut highlights growing investor selectivity in the technology sector.
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Futures at a Glance📈
Futures are mixed as Monday's tech rebound loses steam, with Nasdaq futures slipping while the broader market holds steady. Rising oil prices and renewed AI spending concerns are weighing on sentiment, while traders look ahead to Netflix earnings and fresh housing data for direction.

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What to Watch
Earnings (Premarket):
· GE Aerospace [GE]
· RTX Corporation [RTX]
· 3M Company [MMM]
· Northrop Grumman Corporation [NOC]
· General Motors Company [GM]
Earnings (Aftermarket):
· Netflix, Inc. [NFLX]
· Intuitive Surgical, Inc. [ISRG]
· Chubb Limited [CB]
· Capital One Financial Corporation [COF]
· América Móvil, S.A.B. de C.V. [AMX]
Economic Reports:
· Housing starts (September): 8:30 am
· Pending home sales index (September): 10:00 am
Market Pulse
Oil is back at the center of the inflation debate as Houthi attacks revive supply concerns in the Gulf, complicating the outlook for U.S. interest rates and corporate margins.
Netflix and SpaceX face a major earnings test after Tuesday's close as markets look for profitability signals from streaming, aerospace, and massive technology investments.
AI & Industry
ABB reported a record $12 billion in quarterly orders as demand for data center equipment surged, prompting the engineering giant to raise its full-year sales outlook.
Chinese technology giants placed more than $35 billion in Nvidia chip orders as export restrictions reshaped AI purchasing, although limited supply could prevent most orders from being filled.
Healthcare & Biotech
Roche struck a cancer-drug partnership with China's Hansoh potentially worth over $15 billion as the companies expand antibody-drug development targeting multiple cancers.
Germany's Merck agreed to buy Silence Therapeutics for approximately $1.3 billion to expand its RNA-targeting drug portfolio with treatments for rare blood cancers and other diseases.
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Finance & Deals
Tradeweb agreed to acquire bond-trading platform Trumid for $1.97 billion as the companies combine credit-market technology to connect new bond issuance with secondary trading.
Silgan and American Industrial Partners agreed to buy Trivium Packaging for $3.4 billion to build a larger metal-packaging business serving global consumer brands.
Capital & IPOs
Sea Limited is preparing an IPO for its financial services arm Monee as the company seeks greater flexibility to expand payments, lending, and digital banking.
South Korean AI company Elice plunged 32% in its market debut after raising roughly $150 million in proceeds, highlighting growing skepticism toward data-center infrastructure valuations.
The New York Stock Exchange traces its founding to the 1792 Buttonwood Agreement, signed by 24 brokers beneath a tree on which street?
Movers and Shakers

Alvotech (ALVO) +8%
Alvotech shares jumped in premarket trading after the FDA approved a new manufacturing process for SIMLANDI, its biosimilar to Humira. The upgraded process more than doubles drug substance output per batch without expanding production scale. The efficiency gain frees up manufacturing capacity for other products and strengthens Alvotech's ability to meet growing demand.
Arhaus (ARHS) +7%
Arhaus shares rallied after Piper Sandler upgraded the stock to Overweight from Neutral and raised its price target from $9 to $13. The firm cited improving comparable sales trends, stronger management execution, and opportunities for margin recovery. The upgrade followed last week's analyst event highlighting the furniture retailer's growth initiatives.
Mirion Technologies (MIR) -10%
Mirion shares tumbled in premarket trading ahead of its third-quarter earnings report next week. The radiation detection company reported nearly 20% revenue growth in Q2, but organic growth was just 1.2%, raising concerns about its reliance on acquisitions. No fresh company-specific announcement has been confirmed as the catalyst behind Tuesday's sharp decline.
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*This ad is sent on behalf of Guardian Financial Publishing LLC, doing business as Stable Financial Publishing, 1013 Centre Road Suite 403-D, Wilmington, DE 19805. Nothing here is investment, financial, legal, or tax advice, and it is not a recommendation or solicitation to buy or sell any security. Investing involves substantial risk, including loss of principal; small-cap and low-priced stocks carry particular risk, including the possible loss of your entire investment. Past performance does not guarantee future results. Stable Financial Publishing, its owners, employees and contributors may hold positions in securities mentioned and may trade them at any time. References to Elon Musk and SpaceX are for informational purposes only; Stable Financial Publishing is not affiliated with, endorsed by, or sponsored by Elon Musk or SpaceX. Privacy: https://guardian.pub/privacy-policy/ · Terms: https://guardian.pub/terms-of-service/
Everything Else
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🏢 Keppel agreed to sell a majority stake in its Singapore office tower business to Keppel REIT for approximately $477 million, freeing up capital for reinvestment.
🧪 Solstice Advanced Materials attracted activist investor Starboard Value, which is pushing for cost cuts after the company's failed $14.5 billion acquisition of Element Solutions.
⛏️ New Hope announced a $1.8 billion acquisition of rival coal producer Malabar Resources, expanding its Australian mining operations through an all-share deal.
📦 Amazon jumped nearly 5% Monday following a bullish Morgan Stanley upgrade, helping lead a rebound in U.S. technology shares.
🤖 Elice Group plunged on its market debut, with the South Korean AI infrastructure company's shares falling nearly 30% amid concerns about technology valuations.
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— Adam Garcia
Elite Trade Club
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